While cannabis, which is also known as “marijuana” among the people, was a narcotic plant and its cultivation was prohibited in many countries, these prohibitions on cannabis have started to be broken one by one with the researches carried out in recent years. Well, what happened to cannabis, which we know as harmful all this time and which has been placed in the memory of the society with the word “marijuana”, has started to become useful today? What do researches on the use of cannabis in the treatment of chronic pain say?
A study conducted at Oxford University found that cannabis use did not reduce chronic pain, but made it more bearable. Researchers found that the active ingredient in cannabis reduces activity in the part of the brain related to pain. However, it was stated that the effectiveness of cannabis against chronic pain varies greatly from person to person. The study at Oxford University was conducted on 12 healthy men. Participants were given 15 milligrams of THC (Tetrahydrocannabinol) pills, the active ingredient in cannabis, or placebos with no effect. The volunteers were then smeared with a normal cream or a burning and bitter chili cream on one leg.
After this, four brain tomographs were taken, showing changes in brain activity as the perception of pain decreased. “The pain caused less discomfort to the patients using THC,” said Michael Lee, head of the team that led the study. Brain tomography also showed less activity in parts of the brain that perceive pain. Lee said that in the future, they could predict who might use cannabis as a pain reliever. Mick Serpell from Glasgow University also emphasized that the research confirmed an already known phenomenon.
Cannabis in the Treatment of Stress, Chronic Pain and Cancer
Cannabis oil is a very powerful oil. Small amounts are enough for it to have a powerful effect on the body and mind. The term cannabis (popularly known as Marijuana) is used to describe the cannabis Sativa plant grown for its strong, sticky glands known as trichomes. These trichomes contain high amounts of tetrahydrocannabinol (called THC), the cannabinoid best known for its psychoactive properties.
Hemp Seed Oil is obtained as a result of pressing beneficial hemp seeds. Although Hemp and Sativa Hemp are from the same strains, the Hemp oil used in the treatment is slightly different. The term cannabis is used to describe a Sativa cannabis plant that contains only trace amounts of THC. It is a plant that is widely grown for industrial uses such as hemp, oil, and topical ointments, also used for clothing, construction, paper, fiber, and more, and more.
It took decades before the therapeutic value of cannabis was realized again after the worldwide ban, and even now its use is rather limited. According to a 2007 scientific review published in A Research on Cannabis Clinical Neuroscience Dialogues, scientists said that despite the mild addiction to cannabis and increased dependence on other abusive substances, the therapeutic value of cannabinoids should be very high when used with cannabis.
Many diseases, such as anorexia, vomiting, pain, inflammation, multiple sclerosis, neurodegenerative disorders, epilepsy, glaucoma, osteoporosis, schizophrenia, cardiovascular disorders, cancer, obesity, and metabolic syndrome-related disorders, can be treated using cannabis products. Although studies are limited due to strict government regulations, a growing number of pediatric patients also seek relief of symptoms with cannabis or cannabinoid therapy.
Cannabis Is Good for Chronic Menstrual Pain
The claim that medical marijuana (cannabis) products, which have been legalized in 29 states in America, can also be used to reduce menstrual discomfort, has been accepted by the state of New York. The marijuana plant, known as cannabis, has been banned in many parts of the world for many years because of its narcotic effects. However, research in recent years has proven that this plant can be good for many diseases. Marijuana, which can be prescribed for ailments such as cancer, AIDS, MS, Parkinson’s diseases and dizziness, nausea, and cramps in 29 states of America, has also been found to reduce menstrual pain and discomfort.
The positive results evidenced by various researches conducted at Jama Network and the National Academy of Science, Engineering, and Medicine indicate that marijuana can also reduce symptoms such as cramps, nausea, and weakness experienced during menstruation. Considering published research on marijuana products, the New York State Senate approved in a decision published in January that medical marijuana can be good for menstrual pain. User reviews are also very positive. Women who have tried the product say that all their ailments disappear within 20 minutes. However, in order for this product to become widespread, it needs to be supported by some scientific research.
The marijuana plant is consumed by drying its leaves and wrapping it like tobacco, but marijuana tinctures used for medical purposes are also very common in the USA. Products that can be purchased with doctor’s permission in the states where it is legal do not usually cause a lot of intoxication, as they are made entirely for their healing effects. Today, the drugs recommended for menstrual pain are usually anti-inflammatory, antispasmodic-derived painkillers. Considering that marijuana causes similar effects on the whole body, it is obvious that it can be a natural and effective alternative that can be used to reduce the discomfort experienced during the menstrual period.
Cannabis Leaf Is the Remedy for Chronic Rheumatic Pain
Used in fabric and papermaking, hemp relieves rheumatism pain. It has been proven by medical trials that cannabis plants such as hemp can relieve rheumatic joint pain. Pain in the areas of cannabis dropped through an oral spray. Researchers noted that as a result of taking the drug as a mouth spray, movement and rest became less painful, as well as improved sleep quality. The scientists, who say that the most important role in the treatment is the ‘high’ mood caused by drugs, now want to support their findings with larger-scale trials and thus help 600,000 rheumatic patients in the UK.
The medical journal published the results of the research conducted by a group of scientists headed by David Blake, a bone professor from Bath University, and described the results as statistically significant. In the pain rating of 0-10, where zero means no pain, it was determined that the pain of those who took cannabis by mouth spray decreased from seven to 4.8. Cannabis is the oldest source of vegetable raw materials in human history. The fibers in the stems are used in yarn, weaving, and fabric production, and the pulp part is used in papermaking. Its homeland is Central Asia. It is grown and cultivated in temperate and tropical regions. It is an annual plant with a hard, bushy, hollow stem, palmate leaves. Its fibers are durable and quite long. The fibers of the genus are used in coarse weaving. Its flowers are yellow and in clusters.
Since drugs are also obtained from this plant, also known as cannabis or hemp grass, its cultivation is restricted. Its leaves have used in medicine and cosmetics. Its seed is used as fuel because it is highly oily and nutritious. Its seeds are also used in soap making and paint making. Its seeds are one of the favorite food of birds. Other benefits of cannabis are as follows:
- It is soothing and stimulating.
- It alleviates rheumatism pains if the leaves are boiled and mashed.
- It removes phlegm.
- It improves stomach and intestinal diseases.
- It is beneficial against urinary tract infections.
- It is also useful in prostate complaints.
After the seeds are crushed, it is infused in hot milk and filtered or used as a paste with honey. There are also narcotic raw materials and hemp oil in hemp. It should never be overused. Marijuana that is derived from cannabis causes premature dementia in the brain as well as causing hallucinations and mental illnesses with its negative effects on mental health.
Cannabis for Chronic Pain in Pets
People have been using medical marijuana to relieve chronic pain for the past 10 years. Well, can this weed alleviate the pain of sick animals? According to the New York Times, several companies have launched cannabis-containing products designed for their close friends. Apparently, pet owners use products for cats, dogs, and other breeds as painkillers, reducing sickness attacks and even reducing tantrums. Lisa Moses, a veterinarian who runs an animal pain clinic at MSPCA (Angell Medical Animal Center in Boston) says: “People are constantly asking me about this. There are many people and veterinarians here who think these supplements are good for their pets. ”
Of course, this is a personal opinion. Neither a cat nor a dog nor science can tell you that. We have no studies to show that these products are effective or safe. Worse, Moses said, we have no way of knowing how great the risk we took. While the idea that something that affects people also affects animals made sense, Sarah Moore, a veterinarian at Ohio University says. It turned out that animals that secretly took products from their owners had greater health problems. There are various examples of this caused by the incidental usage of cannabis by pets; these pets can become really ill. So it isn’t on the whole correct to give them clinical or recreational cannabis.
Symptoms such as weakness, vomiting, drooling, palpitations, or contractions in the hind legs, dilated pupils or urinary incontinence are observed. In addition, the animals are at risk of falling into a coma or even dying. However, fortunately, this is a rare occurrence. Typically, the main active ingredient in cannabis is not tetrahydrocannabinol (THC). Instead, products (edible oil, tincture, powder, piece of tobacco) contain cannabidiol (CBD), another chemical form of hemp. Many of them (Canna-Pet or Treatibles) are made from the ‘jute’ plant, a variety of cannabis. This substance is grown for cannabis and is also sold as a supplement.
CBD is not a psychoactive substance, but it may have some benefits. Researchers are investigating whether CBD can be a treatment method for problems such as paralysis, pain, and inflammation. But nobody knows exactly what effects they have on humans or animals. We have no studies or information on the amount, dose, administration frequency, or even what ailment it is useful for. Another issue is digestion. We realize that canines process cannabis uniquely in contrast to people, and that makes things much more convoluted. While a few organizations have developed that offer cannabis available to be purchased, Moses said this upset him a great deal since they have no information about its harmfulness.
So what does the Food and Drug Administration say to this situation? The FDA does not approve of the use of cannabis for animals, nor for the administration of CBD-containing supplements to animals. That’s why there are no standard rules about how these products interact with the medicines the animals take and how they should be used. It is difficult to know exactly what is in the content of each supplement. This information may not be written on the package, or even disclosed when a doctor or consumer asks directly, as most companies keep material content hidden, Moore said.
Considering that different species react differently to what they eat depending on their metabolism, things are getting more and more misleading and risky. Felines, for instance, are known to have the oddest known digestion for medications and synthetics. Their bodies balance the toxin in an unexpected manner in comparison to different species. That is the reason we must be more cautious. Herbivores can be a totally extraordinary issue, in any case. Finding the right amount of cannabis for pets whose body systems work thusly is absolutely not exactly equivalent to finding the right amount for carnivores. You truly need information for various types.
Different species of animals have different metabolisms. Cats, dogs, and rabbits may react completely differently to cannabis-containing products. They dislike individuals, they can’t quit taking medications when they feel bad. Apparently, it is seen as inevitable that pet owners will try all kinds of ways for their beloved friends and sooner or later return to these easy-to-use products. For these people, Moore recommends that you take caution and make sure your pet is carefully observed when it behaves in a bad mood.
In the meantime, standard pain relievers such as Quellin or Onsior used in the physical therapy process may be among the best options to relieve your pet’s chronic pain. Before anything turns out badly, it merits seeing a veterinarian for investigating all the new alternatives. This is truly encouraging; we can sort out how certain mixes (cannabis) ought to be utilized to treat pets having chronic pain. However, in my opinion, we are now far from this situation.
Chronic Pain Reliever Cannabis Project in Chile
You will be in trouble if you ask the authorities for permission to grow 750 root females in the residential neighborhood of capital in many countries around the world. However, in Chile, the state has approved such a project. Female cannabis, the raw material of marijuana, will be grown in the La Florida region of the capital Santiago. The first crop will be taken next April and the oil will be used as a pain reliever for 200 cancer patients. Discussions on cannabis use in Latin America concentrated on Uruguay. Uruguay turned into the main nation on the planet to legitimize the development, deal, and utilization of cannabis. But in Chile, the authorities took a different approach and allowed the use of cannabis for medical purposes only.
“We don’t want to get into a discussion about the personal use of cannabis. Let’s just talk about its use for medical purposes. The point is to offer cancer patients a natural, healthier, and cheaper pain reliever,” says Rodolfo Carter, Mayor of La Florida. The Daya Foundation will manage the project. A clinical trial will also be conducted on the use of cannabis as a pain reliever. Nicolas Dormal, one of the founders of the foundation, says “We hope that everyone can buy the painkiller we can produce from cannabis, even those who cannot afford it. But for now, we will focus on the first 200 patients. In addition to this project, the Chilean authorities also gave a sick woman permission to import drugs made from cannabis.
Cecilia Heyder was diagnosed with Lupus, an immune system disease, five years ago. 18 months later, he had breast cancer. She had her breast removed with surgery and received radiotherapy and chemotherapy treatment. He took dozens of pain relievers given to cancer patients, but Heyder says the side effects of these drugs are devastating. Heyder says, “The pain was unbearable. I wanted to hit my head against the walls. I could not walk. I was in a wheelchair. When the children entered my bedroom, I was not able to reach out of the bed and kiss them.” Heyder bought some cannabis and brewed his tea at a point where he felt helpless.
She explains that she felt the effect immediately and was more effective than any other pain reliever she took. She later says he tried to find drugs made from cannabis but could not find them in his country. For this reason, she started lobbying the government to obtain import permits. She got permission to import last August and medicines from Europe last month. This is the first legal import of drugs made from cannabis into Latin America, according to Chilean officials. But the drugs are expensive. Medications for a month’s treatment cost 2 thousand dollars. Heyder says she raised money by campaigning on social media, but only got the money for three months of medicine.
Chilean officials say that if she does not get cannabis drugs for free, she will have to buy cannabis illegally from the street. Heyder says am I going to go to the streets again and fear being arrested? I don’t want to do that. The venture in La Florida expects to create less expensive medications as an option in contrast to imported medications for cancer patients like Cecilia. If the project is successful, it can also be used to provide medicines, especially to those suffering from other diseases such as epilepsy. Lucas Riffo is only six months old. He was born with severe epilepsy. He had 300 epileptic seizures a day. Her parents, Gabriela and Jorge, say that known epilepsy medicines don’t work.
Later, Lucas tried the oil they made illegally from the female marijuana they raised themselves. Jorge Riffo explains that the improvement in Lucas’ health when given oil is tremendous. “We first started to give in small doses. We carefully watched his pulse and breathing. When he took the oil, he was always fine. Then we increased the amount and he started to have no seizures for five or six hours. No previous drug has worked so well,” says Riffo. But not everyone is convinced of the benefits of cannabis. Some doctors point out that cannabis is addictive and can cause psychological problems.
The World Health Organization warns that cannabis impairs the ability to learn and can make schizophrenia worse. According to the organization, more research needs to be done to determine the medical benefits of cannabis. There is also a security dimension. “Who or what can stop the medical marijuana market from falling into the hands of smugglers?” In Florida, specialists encompassed the female cannabis developing region with an electric wall to forestall the burglary of the plants. Nicolas Dormal of the Daya Foundation says marijuana should be given a chance, despite the potential health and safety risks.
“Marijuana has some negative side effects, but it’s really minor compared to other legitimate drugs. If you put the pros and cons on a scale, cannabis is much better than conventional drugs,” says Dormal. For Cecilia Heyder, whose doctors say she has only a few months to live, the choice is clear. “Marijuana doesn’t cure my cancer or lupus, but it reduces my pain. That’s all I want,” she says.
High Demand for Medical Cannabis for Chronic Pain
Cannabis is a savior for patients with severe pain. After the release of medical cannabis in Germany, heavy demand cannot be met. There has been intense debate about legalizing the use of cannabis in the medical field in Germany. The legal regulation required for seriously ill people to purchase quality cannabis produced under state control in exchange for a doctor’s prescription was made at the beginning of last year, and the medical use and sales of cannabis in pharmacies began in Germany in March 2017.
However, it takes a certain amount of time for cannabis seeds to turn into flowers and start the production phase. Christoph Schäkermann, a German who was diagnosed with multiple sclerosis (MS) disease in 2015, first received a cannabis prescription from his doctor in August 2017 after his doctor’s diagnosis. However, when he went to the pharmacy, he was told that cannabis would only reach his hands in October. The fact that cannabis could not be found in the pharmacy at that time and the sickness insurance refused to bear the costs made it quite difficult to treat the man who already lived on social state aid.
“Cannabis ensures that I have a correct daily rhythm of life and also allows me to overcome all my pains and cramps. When I have pain or mobility problems, I feel much better when using cannabis. I can cope much better with pain,” says Christoph Schäkermann. . Under the new law in Germany, seriously ill patients have the right to purchase medical cannabis from the pharmacy without special authorization. Dried leaves or hemp extract integrated into the drug can be used against complaints such as spastic contractions, chronic pain, and nerve pain in diseases such as multiple sclerosis (MS) and rheumatism. Cannabis also has an appetizing feature in diseases such as cancer and AIDS. However, the positive effects of cannabis extract have not yet been fully researched scientifically.
Although, until now, most of the patients in Germany have covered the costs of treatment with cannabis from their own pockets and the costs of their health insurances have only been borne in individual cases, with the change in the law, health insurances are now obliged to cover the treatment costs. The German Pharmacists Association (ABDA) announced that in the first half of 2017, 10 thousand 600 units of cannabis leaves were given to patients with a doctor’s prescription. However, the numbers exploded in a short time. While 560 prescriptions were given from doctors last March, this number increased to approximately 5 thousand in June. In addition, it was reported that 12,500 ready-made drugs containing hemp extract were delivered to patients. A bottleneck in this area since last summer is attributed to intense demand.
Entrepreneurs named David Henn and Niklas Kuparanis discovered this young market on time and established their companies. David Henn founded the company “Cannamedical Pharma” in November 2016, two months before the “Cannabis Act” for medical purposes was passed in Germany. This firm is one of four import companies that have received a license from the Federal Agency for Narcotics to ship medicinal cannabis to Germany. They started out as a small office in the center of Cologne but are aiming to become the number one trading partner of cannabis producers worldwide in the future.
As the need for medical cannabis has surged, importers and manufacturers are faced with a major challenge, with one goal for the executives of Cannamedical Pharma: to continue to meet patients’ needs for high-quality medical cannabis despite the supply bottleneck. “At the moment there is only one producer in Europe that produces in the Netherlands. This single producer has to meet the growing demand for medical cannabis in Europe, but it is not possible to realize it,” says Niklas Kuparanis, sales manager of Cannamedical. Kuparanis emphasizes that looking back, he could say that the need for medical cannabis in Germany is underestimated, another problem is the question of liquidity, all orders from the Netherlands must be paid in advance to the Medical Cannabis Office (OMC) there.
Cannamedical Pharma officials expect many things to change and their business to grow further in 2018. They explain that they will work with a partner with whom they can cooperate in the long term and receive a supply guarantee, thus meeting all medical cannabis needs in Germany. Cannamedical Pharma will import products from a Canadian company in the future. Companies producing cannabis content in Canada, the USA, and Israel have billion-dollar markets. Canada and the Netherlands are the main shipping countries in Germany.
Importers calculate that in 2018, they will meet the needs of 30,000 serious patients who will need medical cannabis in Germany. It is estimated that there are 10 thousand patients in need of medical cannabis under general health insurance, 20 thousand under private health insurance, and around 30 thousand patients who make private payments from their own pockets. Cannamedical’s sales manager Niklas Kuparanis states that in 2018, approximately 22 tons of cannabis will be imported to meet the needs of only 30 thousand patients. Kuuparanis adds that the warehouse where the cannabis will be collected will be in a top-secret location in central Germany.
Cannabis producers are obliged to fulfill the GMP (Good Manufacturing Practice) standards, which is the quality standard in terms of quality guarantee, production stages, and production site. Because what we are talking about is the highest quality cannabis medicine needed by serious patients. The Cannamedical firm actually wants to produce itself and sees a commercial area here. The Cannabis Agency of the Federal Narcotics Agency controls production in Germany. The tender conditions of this agency are problematic at one point: The producer must prove that they have cultivated or produced cannabis before. However, cannabis cultivation is not legal in Germany!
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